I would prefer thinner profile than mud-grippers for a long trip, couple them with a decent air-compressor allows you to set pressures for sand and mud conditions. Wide tyres create road noise that can be annoying over long distances. Thinner profile brings a lot of lite-truck tyres into play in which there are 10-ply models. I swear by 10-ply, 8 minimum. If you plan a lot of sand driving get a set of bead-lockers.
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