Even if you are riding south from Medellin, you can do it by Supia, just after the toll in La Felisa intead you take left to Irra, take Right, you will find Supia, Riosucio, Anserma, La Virginia and you are in the main road again, it's little longer but the sightseeing is much much better and the road is in good condition, not crowded with trucks, don't do it at night.
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