Welcome to the HUBB!
No doubt you're already aware that all reliable answers start with "it depends," right? Because....it depends. Between Mendoza--a day's ride from Santiago--and Ushuaia took me about a week, but of course I was pushing it to some extent and ignoring many of the sights. You could do it a bit quicker, but you could also go a LOT more slowly. Returning northward after an Antarctic trip, I cut across to the Caraterra Austral, Torres del Paine, El Chaltén and all the usual attractions, and spent about a month or so before making it back to B.A., which is roughly equivalent to Santiago.
Heading south I did little aside from ride (and curse the wind), and returning north I left the bike behind for day hikes, overnights, and a variety of other distractions. You're aiming somewhere between those parameters, but 25 days is not much time unless you're seriously opposed to exploring off the bike from time to time. Note that I'm not even allowing for breakdowns or maintenance, but you probably know how that goes. Nor did you say what you're planning to do with the bike afterward, but if that needs to be factored in you're short on time again no matter what.
I'd think about skipping Ushuaia, since the payback for the substantial added mileage is a bit scant at times. That would leave you a reasonable amount of time, but still far from excessive.
Hope that's helpful.
Mark
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