Not much wrong with the weather you may expect, it is still late summer . Do try to go to the Grand Canyon South Rim from Williams or Flagstaff, In Arizona, mind you, or take the north approach to the North Rim from the Utah approach ( Las Vegas NV, St.George UT then east through the Utah parks to North Rim entrance roads)
May I also suggest that unless you have some personal reason for wanting to see Sandusky Ohio you might consider going to Detroit or Port Huron Michigan and crossing over into Ontario, Canada and then to Niagara Falls . Canada has the better view points for the falls and this route will make no difference to your schedule. Most tourists wind up going to te Canadian side anyway so you too would probably do the same . From there you can carry on with your list as planned
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