As always depends on many factors but from what you say, you have the freedom to push your boundaries at the moment and Africa is calling to you. I'd lean toward doing the trip that is hard and far away and that a person may not get to again for sometime, if life has it's way and intervenes.
It's fairly easy to get down to Central and South America from where you are, heck you can just ride out your front door. Africa is another level of logistics and planning and cost as you know. Ride there while you can, so you can be a grizzled old guy showing your kids pictures of you ridng in deepest, darkest Africa. Rare are any regrets.
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