I've travelled almost every day for three years with my laptop (Compaq Presario) in the top-case of my bike. Around ~8.000 km/year with the laptop. Normally only on good roads. I have had no problems with it. I carry the laptop in a commercial bag with some kind of foam in the back side. This seems enough ...
About photgraphic cameras, I have had some problems with a reflex camerathat I carried for 8.000 km in my tank bag (this august in Turkey). A couple of small screws on one of my lenses got loose, I suppose because of vibration. I had to periodically re-screw them. Next time I will use a custom made foam protection for the camera/lenses.
Another lens had some oil drops in the inside of the glass. I think the oil leaked from the diaphragm because of vibration or excessive heat. I have heard that excessive heat can also cause some fungus to grow inside your lenses. Protecting equipment/film from heat can be more difficult if travelling under the sun in warm countries.
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