Sidecars regularly run car tyres. There is no more or less risk of a puncture or sidewall damage they just last about 10 times longer when run without any lean over.
If it's a single sided swingarm with bolt on wheels, you have two options. Have an adapter made so you can fit a standard size wheel all round just like we do with BMW's. You might have to change the gearing and shock in the worst case. Plan B is to hope the bolt PCD is standard and buy a spacesaver spare. You won't be doing much over 40 mph with one corner at the wrong height by an inch or so, but you can at least pick your spot to fit it.
Andy
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