Hi Galen,
I agree with the others recording to handle bar positioning, relaxing and stretching. I ride througout the year no matter what the weather forecast is telling me. Therefore I strongly recommend regular exercise to warm you up. Furthermore check your position on the bike and your screen ( if fitted ). A different screen could reduce the pressure on your head an shoulder area. Also give a check to your garment. It should fit properly but give you a certain freedom of movement. A painkiller as you mentioned is ok for short time use if you are on the road but definitly not as a permanent solution. The damage done to your body ( i.e. liver and kidneys ) should not be forgotten.
If nothing helps, make a break BEFORE the pain start i.e. every 60 miles.
See you on the Road
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