most people consider the Garden Route as the ultimate trip to Cape Town. In fact, most of it is rather boring. There are a few sights, eg. the Wild Coast and the "Hole in the Wall" south-east os Umtata/Transkei, but IMHO the more interesting ride is from Durban maybe to Port Edwards and then into the mountains to Maclear area. There, check out Naude's Nek Pass,
the highest pass next to Sani Pass. Turn south to Uitenhage, ride through Baviaans Kloof, cross the Swartberg Pass from north (Prince Albert) to south. On top of the pass visit Gamka Kloof, a cul-de-sac going 60 kms into the boondoks.
The rest to CT is all beautiful, scenic country. So it doesn't make a difference, whether you take the Route 62, or prefer to touch the coast, maybe Cape Agulhas, the southernmost tip of SA.
Enjoy the ride!
Only when we pause to wonder
do we go beyond the limits of our little lives.