It is generally considered that when approaching from Venezuela, that Cucuta is the safest point to cross. That's the way I came, stayed over in San Gil, (lovely), and then headed to BOG, MDN and from there a 2 day ride to Cartagena. I won't know myself until next year, but I believe you are more exposed coming from Ecuador, but enjoy Colombia as much as you can. It was the highlight of 12 countries for me. So much so that I am returning in a couple of months to live there. Just remember that despite how incredibly safe things feel, there lurks a danger, that you won't and hopefully never will encounter, but exists anyway.
How much does a man live, after all?
Does he live a thousand days, or one only?
For a week, or several centuries?
How long does a man spend dying?
What does it mean to say “forever”? - Pablo Neruda