I'll be there as well as a first-timer. I'm only driving over the hill from Durango, but I'll try to at least drive the long way round (um, no pun intended) over Lizard Head and through Telluride.
50 sounds great.
By the way, Silverton's been sunny and cool the last couple of weeks, with occasional mountain showers. Should be great.
Four wheels good. Two wheels better.