Make sure your physician schools you on the anti-malarials use and effectiveness. This is a medication you want to consider seriously if you really will need it or not. Not one ADV rider who has come through Mexico whom I have met has used anti-malarials for Central and South America.
Remember, it's not the malaria here, it's the Dengue.
Funny nobody has mentioned Chagas disease. If you are a worry wart, you better add Chagas to the list!
Seriously, try to think more like this
Instead of thinking like this
Oh, and don't forget Hep B, you'll want to have the series of 3 shots and for sure a Hep A whack of gammaglobulin or whatever they call it.
Why go half way with just the anti-malarials?